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This can lead to fatigue and weakness

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Prior Exercise in Humans Redistributes Intramuscular GLUT4 and Enhances Insulin-Stimulated Sarcolemmal and Endosomal GLUT4 Translocation. Krentz, Nicole A

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These aspects include neuronal adaptations centered around synchronized recruitment of motor neurons in several different muscle groups, matching muscle fibre recruitment to exercise intensity, learning new motor patterns involving multiple muscle groups or muscles in isolation (Carroll et al., 2001